In 2021 World Health Organization gave guidance to monitor low-level viremia, the guidelines have been designed to cater for health facilities with capacity to utilize plasma and dried blood spot (DBS) samples at suppression cut off points of 200 copies/mL and 400 copies/mL respectively.

Ministry of Health revised the Consolidated Guidelines for prevention and Treatment of HIV in Uganda November 2022 and adopted the changes.

Starting November 7, 2023, the suppression cut off is 200 cp/ml for Plasma and 400 cp/ml for DBS. The suppression cut off for both Plasma and DBS prior to November 7, 2023 remains 1000 cp/ml.